Tottenham have disposed Chelsea as third favourites to win the title after overtaking them in the Premier League table with a fantastic 3-1 at Wembley.
Mauricio Pochettino's men burst out of the blocks and completely dominated the early stages, taking a 2-0 lead inside 16 minutes thanks to Dele Alli's header and Harry Kane's long-range effort.
Spurs registered no fewer than 18 shots at goal throughout the match with half of those being on target, perhaps none more significant than Son Heung-Min's fine finish into the bottom corner after a superb run from down the right wing.
Olivier Giroud grabbed a consolation for Chelsea late on but the victory for Tottenham was fully deserved and it was one that inflicted Maurizio Sarri's first defeat as Blues manager. Spurs can be backed at 32.00 in the Premier League Winner market with Chelsea now out at 65.00
Man City and Liverpool in comfortable wins
Manchester City shortened slightly to 1.28 to retain their title while Liverpool remain 6.00 second favourites after both teams recorded straightforward away wins.
City's victory at West Ham was seemingly never in doubt from just the 11th minute when David Silva put them in front, and Pep Guardiola's men would go on to score three more through Raheem Sterling and a brace from man of the match Leroy Sane.
The Reds had to wait until the second half to break the deadlock but once Mo Salah put Jurgen Klopp's men in front the result seemed inevitable, though Watford did have strong claims for a penalty before Salah's opener when Andy Robertson appeared to foul Will Hughes.
Trent Alexander-Arnold's stunning free-kick and a tap-in from Roberto Firminocompleted a great day for Liverpool who stay two points behind City at the top of the table.
Another poor day for boring United
Jose Mourinho's Manchester United were held to a goalless draw at home to Crystal Palace in a match that had sections of the Old Trafford crowd booing as the final whistle blew.
Mourinho had earlier insisted that his side were capable of being in the top four by Christmas, but after the game he accused his players of not having enough heart as they failed to win for the sixth time in just nine games this season in front of their home fans.
Despite only drawing United moved up to seventh in the table though they themselves were overtaken by Everton who beat Cardiff at Goodison Park thanks to a solitary Gylfi Sigurdsson goal.
In the Top 6 Finish market United can be backed at 1.36, while Everton trade at 4.80.
Claudio makes instant impact
Fulham moved off the foot of the table with an entertaining 3-2 win over Southampton in Claudio Ranieri's first game in charge of the Cottagers.
The victory means Fulham move up one place to 19th, relegating Huddersfield to rock bottom, though they are still one of the three most fancied clubs in the Relegation market, trading at 2.02; The Terriers can be baked at 1.52 while Cardiff are as short as 1.44following their narrow defeat at Everton.
Southampton slipped to 17th in the table following defeat at Craven Cottage and it seems Mark Hughes is now in a fight to save his job. The Saints can be backed at 4.30 to go down.